Nov . 02, 2026 02:04 Back to list

HPV Detection Kit Comparison: 2+12 DNA and 15 E6/E7 mRNA Formats


Taizhou Cowingene Biotech Co.,Ltd.'s HPV (2+12) and HPV 15 E6/E7 Gene mRNA Detection Kits are both lyophilized, 48-test PCR kits with a 100 Copies/mL limit of detection and 2-30°C storage for 18 months. The main purchasing choice is the detection target: the HPV (2+12) kit identifies HPV 16 and 18 separately within a 14-type high-risk panel, while the mRNA kit detects 15 high-risk types in a single analysis.

HPV Detection Kit Comparison: 2+12 DNA and 15 E6/E7 mRNA Formats
Illustration for reference; see the product page for actual photos and specifications.
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Cowingene HPV (2+12) Detection Kit (Lyophilized)

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Cowingene HPV 15 E6/E7 Gene mRNA Detection Kit (Lyophilized)

The two kits address different HPV testing priorities. The Cowingene HPV (2+12) Detection Kit (Lyophilized) uses PCR to qualitatively detect HPV DNA and separately identifies types 16 and 18, with the other 12 high-risk types detected together. The Cowingene HPV 15 E6/E7 Gene mRNA Detection Kit (Lyophilized) uses PCR to qualitatively detect HPV mRNA from 15 high-risk types in one analysis.

For a laboratory choosing an hpv detection kit, the practical decision is whether the workflow needs separate HPV 16 and 18 typing from a DNA target or a 15-type E6/E7 mRNA panel. The two products share several operating specifications, so the target design should lead the selection.

Side-by-side specifications

CriterionCowingene HPV (2+12) Detection Kit (Lyophilized)Cowingene HPV 15 E6/E7 Gene mRNA Detection Kit (Lyophilized)
Detection targetHPV DNA; HPV 16 and 18 are typed separately, while 12 other high-risk types are detected togetherHPV mRNA from 15 high-risk types in one analysis
High-risk type coverage14 types15 types
Validated specimensUrine, cervical swab, vaginal swab, urethral swab and residual LBC specimenUrine, cervical swab, vaginal swab, urethral swab and residual LBC specimen
Package size and format48 tests/kit, lyophilized48 tests/kit, lyophilized
Storage and shelf life2-30°C for 18 months2-30°C for 18 months
Limit of detection100 Copies/mL100 Copies/mL
Compatible instrumentsOpen real-time PCR systems with FAM, VIC/HEX, ROX and CY5 channels, including ABI 7500, Roche 480 and Bio-Rad CFX96Open real-time PCR systems with FAM, VIC/HEX, ROX and CY5 channels, including ABI 7500, Roche 480 and Bio-Rad CFX96
PrecisionInter- and intra-day, inter- and intra-batch, and different operator/site %CV all ≤5.0% for HPV 16, 18 and the other 12 typesInter- and intra-day, inter- and intra-batch, and different operator/site %CV all ≤5.0%

Where the test designs differ

The HPV (2+12) kit suits a laboratory that needs separate reporting for HPV 16 and HPV 18 while screening the remaining 12 covered high-risk types as a group. Its DNA target covers 14 types, and the validated specimen list includes urine, cervical, vaginal and urethral swabs plus residual LBC specimens.

The HPV 15 E6/E7 Gene mRNA kit uses an mRNA target and covers 15 high-risk types in one analysis. It accepts the same five specimen categories listed for the HPV (2+12) kit, so a laboratory can compare the target design without changing its listed specimen range.

Match the kit to the reporting requirement. Choose the HPV (2+12) format when separate 16 and 18 typing is the central requirement. Choose the 15 E6/E7 mRNA format when the laboratory wants the listed 15-type mRNA panel.

Shared workflow and lab fit

Both kits are lyophilized and supplied as 48 tests per kit. Their stated storage range is 2-30°C for 18 months, and both have a 100 Copies/mL limit of detection. These common specifications support a like-for-like review of inventory planning and instrument fit.

Both products are designed for open real-time PCR instruments using FAM, VIC/HEX, ROX and CY5 channels. A laboratory using an ABI 7500, Roche 480 or Bio-Rad CFX96 can use the listed instrument compatibility as a starting point for its platform check. The workflow also depends on the laboratory's specimen collection and extraction setup, so procurement teams should align the selected kit with their existing sample handling process.

For a screening program receiving urine and cervical swabs, either kit matches the listed specimen range. The decision then returns to the requested target and reporting format. Send the laboratory's PCR instrument model, specimen mix and required HPV genotype reporting format to Taizhou Cowingene Biotech Co.,Ltd. when requesting a quotation or implementation review.

The company

Taizhou Cowingene Biotech Co.,Ltd.

As a young and dynamic company, we specialize in developing and manufacturing molecular POCT in vitro diagnostic reagents. With a professional team and a spirit of innovation, we are committed to advancing health management to be more efficient, accessible, and intelligent—becoming a trusted partner in the field of molecular diagnostics..…

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